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Procerin Research Study Backround


Product Description
  • Procerin comes in a convenient tablet form and topical solution that are used in combination daily for the nutritional therapy of male hair loss. Procerin is a natural supplement available without a prescription. While there are several causes of hair loss, Procerin (topical and tablet together) is effective in reversing hair loss in some men caused by androgenetic alopecia, the most common cause of male hair loss. Androgenetic Alopecia (AGA) results in thinning hair and the familiar receding hairline (or widow's peak.)  AGA afflicts approximately 50% of men over the age of 40.  It is characterized by a progressive miniaturization of scalp hair follicles in predisposed individuals.  AGA hair loss involves a genetically predetermined sensitivity to the effects of the androgenic hormone dihydrotestosterone, or DHT, in certain scalp hair follicles. DHT is believed to shorten the growth, or anagen, phase of the hair cycle, causing the miniaturization of the follicles.
  • Speedwinds Nutrition, Inc. has developed this combination of supplements formulated with natural ingredients known to block production of DHT, a major cause of hair loss in men. The active product ingredients illustrated in figure 1 are known DHT inhibitors and are found in the topical solution and nutritional supplement.  Illustrated in figure 2 is product ingredient list.
Figure 1:
  • Saw Palmetto (serenoa repens). Serenoa repens berries grow naturally, with the extract claiming to be an androgen inhibitor of 5aR to inhibit DHT production, mainly claimed for use in prostate problems.  Saw palmetto oil is an accepted use for benign prostate hyperplasia in men. It appears to interact with various sex hormones, including dihydrotestoseteron (DHT). DHT is produced from testosterone by enzyme 5-alpha-reductase. Like most enzymes, it can be inhibited. Saw palmetto is believed to have a similar mechanism of action to the anti-androgenic drug finasteride (Propecia), which has been used in low doses for hair loss.
  • Zinc A lot has been claimed about zinc for use in various diseases, including topical use for acne, another androgen related problem. Specific forms of zinc, i.e., zinc acetate, zinc sulfate, and others, have various properties that promote wound healing, help treat acne, and promote hair growth.  Also, Zinc can boost thyroid function and reduce hair loss that comes from an under active thyroid.  Zinc can also affect the levels of androgens, the hormones involved in some form of genetic hair loss. Zinc sulfate was found to be an inhibitor of DHT production
  • Vitamin B6 (Pyroxidine) helps to create melanin, which gives hair its color and             promotes healthy hair.
  • Magnesium Through laboratory experiments for hair loss, scientists have seen a decrease in thinning hair in lab animals. The results demonstrated that a diet low in magnesium cause hair loss in patches.

Figure 2:

Procerin For Men – Herbal Supplement Tablet

Procerin is an all-natural supplement, formulated specifically for men to combat hair loss and assist in re-growth.

Directions:  Take 1 tablet with water each morning and 2 tablets each night before sleeping.  If stomach discomfort occurs, take with food.

Consult your physician before using if you are currently taking a MAOI inhibitor.  Keep out of reach of children.  Do not use if safety seal is broken or missing.

These statements have not been evaluated by the Food & Drug Administration.  This product is not intended to diagnose, treat, cure or prevent any disease.

 Procerin Supplement Facts

 

Procerin For Men - XT Topical Serum

Directions: Shake vigorously before use.  Apply 1ml to the affected and surrounding areas of the scalp twice daily.  Gently massage into the scalp.  Allow 10 seconds to dry, then style hair as usual.  Do not wash hair for at least 4 hours.  For best results use daily in conjunction with Procerin tablets. 

Caution: For external use only, keep out of reach of children.  Avoid contact with eyes.  In case of accidental ingestion, seek professional assistance immediately.  If scalp redness or irritation occurs, use only once daily. 

Ingredients: SD Alcohol 40, Polysorbate 20, Purified Water, Oleic Acid, Linoleic Acid, Alpha Linolenic Acid, Azelaic Acid, Evening Primrose Oil, Avocado Oil, Saw Palmetto Extract, Grape Seed Extract (Procyanidin Oligomers), Gamma Linolenic Acid, Pygeum Bark Extract, Stinging Nettle Leaf Extract, Tocopherol (Vitamin E), Zinc Sulfate, Pyridoxine (Vitamin B6). 

Active ingredients in Procerin have had supportive studies relating to hair growth and or the blocking of DHT.

  • The prominent active ingredients of Procerin have been proven to help block DHT  (DHT is the chemical which is said to cause hair loss in men) and combat the effects of hair loss and thinning hair. The Procerin package will be positioned as a dietary supplement and topical which slows hair loss and promotes regrowth. 

Clinical Support:
A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-α-Reductase in the Treatment of Androgenetic Alopecia published in The Journal of Alternative and Complementary Medicine resulted in the demonstration of a positive response for the active ingredients utilized in Procerin and other DHT inhibiting dietary supplements currently on the market.  (The Journal of Alternative and Complementary Medicine. 2002, 8(2): 143-152.)

Other proprietary ingredients like Gotu Kola are known to increase blood flow, Nettles are known as an anti-inflammatory and have been used to alter the same mechanism that affect the aging prostate as those in hair loss.  Most of the ingredients in Procerin have been shown to assist in hair growth in one way or another.

The clinical trials submitted to the FDA provide strong evidence as to the Procerin product’s efficacy and safety. The same is reported in this Research Study.  There were no reported serious adverse events during the Procerin study nor are they expected in the post-study follow-up.

Results from the Procerin Research Study

During the study participants completed a number of questionnaires the answers to which are summarized below in Table 1. and Table 2.

Table 1   Exit Questionnaire Summary

Question Strongly Agree Agree Neutral Disagree Strongly Disagree
Effective in helping to slow hair loss 5 10 5 1 0
Easy to use 4 6 3 3 0
           
Would Recommend to Others 6 8 6 1 0

Table  2. Overall Satisfaction

Very Satisfied/Satisfied

Somewhat Satisfied

Somewhat Dissatisfied

Dissatisfied

10

9

1

1

Objectives
The key objectives of this study were to:

  1. Solicit user feedback on the Procerin use.
  2. Solicit user feed back on any side effect.
  3. Solicit user feedback on key benefits and key challenges of the Procerin combination use.
  4. Solicit user feedback into labeling, packaging, and instructions.
  5. Solicit user feedback on individual experience of product effectiveness.
  6.  Solicit any photographic evidence of efficacy over 90 days.

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